Symptoms of chronic eczema are characterized by thickening of the skin and hyperpigmentation with itching. Treatment includes removal of causative factors, use of antihistamines and immunosuppressant therapy. 1. In the chronic stage of eczema, the affected skin is often infiltrated and thickened, with a dark red color, sometimes with hyperpigmentation and intense itching. The pattern of lesions is variable, and can be seen as erythema, papules, papules or blisters, and sometimes there will be vesicles and scabs and other phenomena. If secondary infection, it will evolve into pustules or thick scabs, more commonly found on the hands, elbow sockets, calves, feet, and even – to the vulva and anus and other places. 2. The first thing to do is to remove the cause of the disease, people with allergies should try to avoid contact with allergic substances, reduce irritating factors, maintain skin hygiene and regular life. Western medicine can use antihistamines, such as chlorpheniramine, benadryl, etc. to relieve itching and reduce exudation, for serious cases can be added with immunosuppressants, such as tacrolimus ointment topical and so on. If the patient has chronic eczema, or the symptoms persist and do not get better, should go to the hospital in time, follow the doctor’s instructions for treatment, do not self-medication.