Fetal malformations, genetic disorders, and infertility may occur as a result of a noninvasive chromosome 16 excess. 1. Fetal malformations: NVF chromosome 16 excess indicates that there may be an extra chromosome 16 or an extra part of chromosome 16. Either way, there is a risk of fetal developmental malformations, such as a small eye slit, wide eye spacing, and asymmetry of the ears, and other malformations. 2. Genetic diseases: Chromosome 16 excess may lead to genetic diseases at the chromosome level. 3. Infertility: An excess or aneuploidy of chromosome 16 may result in the birth of infertile children, primary amenorrhea and ovarian dysplasia in girls and testicular dysplasia in boys. Although chromosome 16 is partial may indicate fetal dysplasia, but the non-invasive chromosome test itself has some limitations, pregnant women can do amniocentesis under the guidance of the doctor for further examination, to confirm that there is no problem with the fetus.