According to Dukes’ staging of colon cancer, it can be divided into four stages from A to D. In stage A, the depth of tumor infiltration is confined to the intestinal wall without lymph node metastasis and does not break through the plasma muscularis layer; in stage B, the tumor foci break through the plasma muscularis layer and invade the extra-plasma membrane as well as the peripheral tissues of intestinal tract, but there is no lymph node metastasis; in stage C, the tumor invades the whole layer of intestinal tract with lymph node metastasis, which may be metastasized to the pararectal and perimembranous lymph nodes, or the root of the mesenteric arteries. arterial root lymph nodes. stage D tumor lesions are accompanied by distant organ metastasis or extensive infiltration as well as lymph node metastasis, which cannot be surgically resected. Early intermediate stage generally refers to stage A and B, i.e., the tumor is confined to the dry intestinal wall, not penetrating into the deep muscularis propria, and there is no lymph node metastasis, or the tumor invades the plasma membrane layer to form the extra-plasma membrane tissues, and there is no lymph node metastasis. In the early stage, there may be no obvious symptoms, or there may be mild symptoms such as abdominal discomfort, change of bowel habit, etc. In the middle stage, there may be abdominal mass, blood in stool or change of stool character. Colon cancer is a kind of malignant tumor of digestive tract that occurs in colon, with different invasion scope, the treatment principle is also different accordingly. Early and middle stage colon cancer mainly chooses surgical treatment, and after surgery, with radiotherapy and chemotherapy to further kill the cancer cells, etc. Doctors will choose the corresponding treatment according to the specific conditions of patients.