Ear inflammation and pain may be otitis media or otitis externa. If it is acute suppurative otitis media, it can be treated with cefuroxime, etc. If it is acute otitis externa, it can be treated with lomefloxacin ear drops. Different diseases have different treatments, and there is no such thing as a “quick fix” for painful ear infections. 1. Acute suppurative otitis media: this disease is caused by bacterial infection, manifested by ear pus, pain, and even fever. Treatment is mainly anti-infection, can be given systemic drugs such as cefuroxime or amoxicillin clavulanate potassium, etc., allergic to the above drugs, can be given azithromycin and other treatments. At the same time, local drugs such as levofloxacin ear drops can be used to strengthen the anti-infection. 2. Acute otitis externa: diffuse inflammation of the skin of the external auditory canal, mostly due to bacterial infection, manifested as skin edema and pain. The pain of this disease is more obvious, can be given oral ibuprofen and other analgesic treatment, with gastrointestinal ulcers are prohibited. Lomefloxacin ear drops can be given to local anti-infection treatment, serious cases can be treated with systemic antibiotics such as cefaclor. The cause of ear inflammation and pain is also boils in the ear canal, which should be clarified under the guidance of a doctor and reasonably treated. The above drugs need to be used under the guidance of a doctor to avoid serious consequences.