Intrahepatic hyperdense shadow is only an imaging description, whether it is serious or not needs to be analyzed comprehensively with other examinations. Intrahepatic hyperdense shadow is mainly seen in intrahepatic bile duct stones and intrahepatic calcified foci. For intrahepatic bile duct stones and intrahepatic calcified foci, if there is no abnormal symptom, it is usually enough to go to the hospital for regular checkups. However, if clinical symptoms such as epigastric pain, fever, nausea and vomiting occur, further tests such as liver function, tumor markers and MRI are needed to confirm the diagnosis. If it is a malignant tumor such as hepatocellular carcinoma that causes high density shadow in the liver, this situation is more serious and needs timely surgical resection. According to the pathological results, radiotherapy and liver-protecting treatment are also needed to avoid tumor recurrence and metastasis. It is recommended to actively consult the doctor, improve the relevant examination, and standardize the treatment after clear diagnosis.