If a person who has received the rabies vaccine has a fever after the first shot, the second shot can still be given. The rate of fever among all rabies vaccine patients is very low, and if the fever is not a high fever, but just an occasional phenomenon on the day of the injection or the next day, it can usually get better on its own without treatment. Some patients may also have redness and swelling at the injection site, which will resolve on their own. If a fever develops after one injection, the second injection is not given and the effectiveness of rabies vaccination will be greatly reduced. A fever does not usually affect the second shot as long as it does not last more than three days. Of course, if the fever is not a reaction to the rabies vaccine, but rather an attack of another infectious disease, a second shot is not recommended.