Tetanus immunoglobulin is not covered by health insurance, so it is not reimbursable by either employee insurance or rural health insurance. Among the drugs that patients need to use in hospital, only Class A drugs and some Class B drugs can be reimbursed, while tetanus immunoglobulin belongs to the biological agents, which cannot be reimbursed. Tetanus immunoglobulin is a passive immunization that produces an immune effect after inoculation, although it tends to last for a relatively short period of time, usually only 2 to 3 weeks. After the tetanus immunoglobulin injection, most of the vaccinated people have no adverse reactions, but a small number of vaccinated people may experience redness, swelling and pain. In addition, there are certain contraindications to the use of tetanus immunoglobulin, and it is recommended that a specialist be consulted prior to vaccination.