Hepatic parenchymal echogenicity is a manifestation of chronic liver damage, usually combined with decreased liver function. It may be caused by chronic viral hepatitis, liver fibrosis and other diseases, the former belongs to a kind of disease transmitted by body fluids, repeated episodes and prolonged delay will lead to liver function damage, and there is fat deposition in the peritoneum, which is manifested in the roughness of the echogenicity. In daily life, patients should stay away from the environment of tobacco and alcohol, and systematically carry out symptomatic treatment such as antivirus and liver preservation. Normally, it is also necessary to pay attention to increasing dietary nutrition and supplementing high protein food. In addition, it is recommended that patients with rough echogenicity of liver parenchyma should go to the hospital in time and follow the doctor’s instructions for treatment to avoid delaying the condition.