Three years is not a long time to say, but for a patient with advanced colorectal cancer, it is not easy to extend the survival period for three years. Especially when the patient is diagnosed with rectal cancer combined with liver metastasis and nine metastatic lesions on the liver, the hope of long-term survival becomes even more remote. However, three years ago, Professor Peng Jirun, Director of the Department of Surgery of Beijing Jitan Hospital, affiliated with Capital Medical University, performed a different surgery for such a patient, and now three years later, the patient is still alive. In traditional treatment, many surgeons, when treating patients with colorectal cancer combined with liver metastases, may only give patients surgery for colorectal cancer due to their specialties or the hospital’s subspecialty, while often recommending patients to receive chemotherapy in medical oncology for their liver metastases. However, recent studies at home and abroad have shown that, under the conditions allowed, patients with colorectal cancer combined with liver metastases can have their liver tumors removed at the same time or in two stages after surgical removal of the primary colorectal lesions, and as long as the metastatic tumors can be removed, the patients can still have a relatively long-term survival. However, if the patient has multiple liver metastases at the same time and too much liver tissue needs to be removed, which will affect the patient’s liver function, or if the patient’s physical condition is poor and cannot withstand the removal of multiple liver metastases, the surgical resection option will have to be abandoned. The patient mentioned above was faced with such a difficult situation, and this case is still very dangerous in the opinion of Prof. Peng Jirun. At that time, he and his colleagues performed a rectal cancer resection and made another incision in the right upper abdomen to remove several metastatic lesions that had grown together in the right lobe of the liver near the margin. With this method, not only all the remaining liver metastases were inactivated, but also the patient’s normal liver tissues were maximally preserved, and the patient recovered and was discharged from the hospital soon. In fact, if the treatment is carried out according to traditional chemotherapy and other therapies, it is often not very effective for these multiple liver metastases, and many patients may only have a survival period of about six months. For patients with colorectal cancer combined with multiple liver metastases, if the primary lesions are removed and the liver metastases are removed by surgical resection and microwave ablation, combined with post-operative chemotherapy and immunotherapy, the patients can survive longer, which is much better than using chemotherapy or even expensive molecular targeted drugs.