The type of ear drops to be used for otitis media needs to be determined according to the condition of the otitis media. In the case of acute otitis media, it is best to use phenol glycerin ear drops until the eardrum is perforated. If the eardrum is perforated and there is purulent discharge from the external ear canal, you should use sensitive antibiotic ear drops. However, some antibiotics are ototoxic and should not be used as ear drops. There are also some antibiotics that are not suitable for topical use because they are prone to develop resistance. Generally, it is the use of quinolone ear drops such as ofloxacin ear drops, levofloxacin ear drops, and also lomefloxacin ear drops. Before using ear drops, it is necessary to remove purulent secretions from the external ear canal so that the ear drops can be used with good effect.