H. pylori after standardized and systematic treatment, usually about 14 days can be cured. H. pylori is a bacterium that exists in the digestive tract and is highly infectious. The method commonly used clinically to treat H. pylori is anti-H. pylori quadruple therapy. The specific program is a proton pump inhibitor plus a gastric mucosal protective agent plus two antibiotics, commonly used proton pump inhibitors are omeprazole, pantoprazole, commonly used drugs to protect the gastric mucosa are bismuth potassium citrate, bismuth pectin, antibiotics can choose amoxicillin, clarithromycin. Amoxicillin is prohibited for patients with a history of allergy to penicillin. these four drugs are taken together orally for a course of 14 days. carbon 14 breath test is repeated after 4 weeks to check the eradication of Helicobacter pylori. the eradication rate of Helicobacter is still very high, its up to about 85%.