Whether an 80-year-old can have a lung puncture should be determined on a case-by-case basis and can be related to the size and location of the lesion. It is also necessary to consider the underlying condition and whether there are other contraindications. 1. Lung lesion size and location: usually a large diameter lung lesion is easy to perform lung puncture examination; a small diameter lung lesion will be more difficult to perform lung puncture examination. The closer the lung lesion is to the periphery, the easier it is to perform a lung puncture, but lung lesions near the hilum may not be able to be punctured. The size and location of the lesion need to be evaluated by the physician to determine if the lesion is indicated for lung puncture. 2. Basal condition: The physical condition of the 80 year old needs to be considered to determine whether lung puncture can be performed. If the underlying cardiopulmonary function is poor, the risk of pneumothorax during lung puncture is high and lung puncture is not recommended. However, if the underlying cardiopulmonary function is good, most of the time it can be tolerated. 3. Any other contraindications: lung puncture cannot be performed if there is a tendency to bleed due to blood system diseases. If accompanied by acute infarction, puncture biopsy is also usually not recommended. If anticoagulant medication is being taken, it is necessary to assess whether the medication can be discontinued. If they can be stopped, lung puncture can be postponed, but if they must be taken, lung puncture is not recommended.