Minimally invasive treatment of vertebral metastases Cancer can spread from its initial site of appearance to other parts of the body. Tumor cells from the primary site are transferred to other parts of the body through the blood and lymphatic channels, or by other means. The tumor growing at the metastatic site still originates from the primary tumor and has the same cell type as the primary tumor. The term used to describe the spread of a tumor is metastatic tumor. Bone is the most common site of metastasis for malignant tumors other than the lung and liver. About 70-80% of cancer patients eventually develop bone metastases, which are about 35-40 times more common than primary malignant bone tumors and are a frequent problem for orthopedic surgeons. The most common one is prostate cancer, 90% of which can develop bone metastasis, and many patients even have bone metastasis when they are diagnosed. This is followed by breast cancer and lung cancer. Once the metastasis of skeletal system occurs, it is very dangerous. Warning signs: most of the following symptoms are bone metastases: 1. Pain (50%-90%): mostly fixed on one point (local): gradually aggravated, light during the day and heavy at night. In late stage with compression fracture, pain to the thoracic spine and lower back, radiating to the thigh area. Patients often have difficulty walking. Bone pain, initially transient symptoms, persist after progression of the disease and worsen with exercise; 2. Pathological fracture (5%-40%): poor bone stress due to tumor, fracture occurs without obvious trigger or when the trigger is very mild; 3. Hypercalcemia (10%-20%): high level of calcium ions in the blood triggering hypercalcemia, resulting in patients with no appetite, nausea, thirst, fatigue, muscle weakness, irritability, and confusion; 4. Spinal instability and spinal nerve root compression symptoms (<10%): other symptoms include lower extremity paralysis, weakness, urinary and fecal excretion problems, or abdominal paralysis; 5. Bone marrow suppression (<10%) For patients who have had tumors, especially prostate cancer, breast cancer, lung cancer, and Thyroid cancer, etc., patients need to be extra careful if they have low back pain, especially severe pain, which are common primary lesions of metastatic spinal tumors. Of course, all malignant tumors have the potential to metastasize to the spine. Case study: Auntie Zhao, a resident of Harbin, was found to have breast cancer 2 years ago and underwent surgery in a local hospital, but in the last half year, her back pain was bad and good, and the attack was only slightly relieved by physical therapy or plastering. In the past month or so, Auntie Zhao's back pain continued to attack and worsen, acupuncture, massage, plastering, cupping 18 classes of "martial arts" have been used, but the pain was still unbearable, and a variety of painkillers did not stop the pain, and finally, it was so serious that the patient could not walk on the ground, the patient was in pain. Family members rushed to the hospital with him. After the thoracic spine X-ray, thoracic spine MRI examination, found that the thoracic 12 vertebrae bone destruction, Wang Yansong, chief physician finally diagnosed as thoracic spine metastases. And decided to use percutaneous vertebroplasty. Many people do not know enough about bone metastases and consider them as end-stage, so they adopt a negative attitude in treatment and even give up treatment as "terminal disease". With the widespread development of comprehensive treatment and the development and progress of surgery, this old concept should be abandoned, and appropriate surgical treatment has definite effects on reducing pain, improving quality of life and prolonging survival. In the past two decades, many researchers have proposed a variety of minimally invasive treatment options that have gradually become effective in the treatment of patients with spinal metastases, with promising results; PVP has been widely used as a palliative treatment option for spinal metastases because of its efficacy in treating pain caused by spinal metastases and its recognized safety by clinicians. Percutaneous translaminar vertebroplasty (PVP) is a procedure in which bone cement is injected directly into the diseased vertebral body using a percutaneous puncture via the pedicle route to reshape the vertebral body, strengthen the vertebral body, maintain or restore stability of the diseased vertebral body, and reshape the physiological function of the vertebral body. Since then, PVP has been widely used in the treatment of vertebrae. Since then PVP has been widely used for spinal compression fractures caused by various spinal metastases. Bone cement is a medical material used in orthopedic surgery, and it is commonly known as such because of some of its physical properties and its appearance and properties after solidification, which are quite similar to white cement used in construction and decoration. In fact, its proper name is bone cement, and its main component is polymethyl methacrylate. The pain of bone metastases arises due to the destruction of bones by metastatic tumors, the pathological fractures produced and the compression and invasion of nerves by the masses. The principle of intervention for bone metastases should first be to inactivate the tumor, then restore the function of the bone, fix the fracture as much as possible, or strengthen the bone, and in addition, protect the adjacent nerves to achieve pain relief. It has been reported that the efficacy of percutaneous cementoplasty is definite, and more than 85% of patients can get effective pain relief.