Why diabetes always goes hand in hand with obesity

With the improvement of living standards and material conditions, people’s health has been slowly corroded by a variety of high-sugar, high-sweet food, according to the International Diabetes Federation (IDF) statistics, the world’s adult patients with diabetes has reached 425 million people, an average of every 11 people have 1 person suffering from the disease. Among them, the number of people suffering from the disease in China has reached 114 million, with the heaviest burden of diabetes. In recent years, with the increase of obesity rate, the number of people with type 2 diabetes is also increasing. Yet why why does diabetes always go hand in hand with obesity? Because obese people usually have the pathological state of insulin resistance, the so-called insulin resistance is the cell resistance to the action of insulin, resulting in the blood glucose can not be absorbed and utilized. In addition to insulin resistance, obesity is associated with a variety of metabolic disorders, including impaired glucose tolerance, hyperinsulinemia, and atherosclerosis, and slowly insulin production is not enough to lower blood glucose to the normal range, and overt diabetes occurs. The risk of diabetes in people with abdominal-type obesity is much greater than in people with hip-type obesity, the ratio of waist/hip circumference is positively related to the incidence of diabetes, and the incidence of diabetes is higher in overweight people with a BMI (body mass index) ≥ 35. Studies have shown that type 2 diabetes is up to 40 times more prevalent in this population compared to the normal population, which is also intriguing. When such diabetics reduce their BMI to normal levels, the vast majority experience significant improvement in their diabetes symptoms. Currently, the vast majority of diabetics use traditional internal medicine to control their condition, or extracorporeal insulin to stabilize their blood glucose, but either way, they can only temporarily control their blood glucose, but there is no way to prevent the onset of concomitant symptoms. For this condition, weight loss surgery can be tried to treat diabetes. After nearly 20 years of clinical research and observation, more and more clinical evidence confirms that bariatric surgery is an effective treatment for obese diabetes. For example, gastric bypass surgery, known as the “gold standard surgery” for diabetes, is a surgical procedure that reduces the volume of the stomach, shuts down most of the stomach’s functions, and changes the structure of the intestinal tract, thus further reducing the digestive capacity and thus controlling absorption. The reconstruction of the gastrointestinal tract changes the secretion of hormones in the intestinal-islet axis, thus improving glucose metabolism. After decades of clinical validation, a large amount of data confirms that obese type 2 diabetes through weight loss surgery, 60% to 80% of diabetic patients through surgery, can completely relieve diabetes accompanied by hypertension, hyperlipidemia, fatty liver and sleep apnea syndrome and other symptoms, and even long-term maintenance of non-diabetic state.