Women’s menopause generally has no relationship with blood in urine and painful urination. Usually, the main reasons for women’s blood in urine and painful urination are urinary system infection, stones, tuberculosis, tumors and so on. 1. Urinary system infection: it can be divided into pyelonephritis and cystitis, which is caused by pathogens growing and reproducing in the urinary tract. The main symptoms of cystitis are frequent urination, urgency, painful urination, and rarely blood in urine. Pyelonephritis is usually accompanied by systemic symptoms such as fever and low back pain on the basis of frequent urination, urgency, painful urination and blood in urine. 2. Urological tuberculosis: most of them are renal tuberculosis, usually tubercle bacillus enters into the kidney through bloodstream infection, forming multiple tiny foci. Its main clinical manifestations include urinary frequency, urinary urgency, urinary pain, hematuria, pyuria and so on. 3. Urinary stones: it can be divided into renal stones and ureteral stones. Abnormal metabolism of the body, obstruction of the urinary tract, infections, foreign bodies and the use of related drugs are the common factors of stone formation. The main symptoms of the disease are pain in the kidney area, hematuria, which may be accompanied by frequent urination, urinary urgency, urinary pain and other symptoms. 4. Urological system tumor: renal tumors include malignant tumors such as renal cell carcinoma, nephroblastoma and benign tumors such as vascular smooth muscle lipoma. The cause of this disease is not clear, mostly related to smoking, obesity, high blood pressure and other factors, and its symptoms usually include hematuria, pain in kidney area and lumps. Symptoms of painful urination, blood in the urine is recommended to go to the hospital in time to improve the examination, to clarify the cause of the disease, with the help of the doctor for treatment.