The sudden appearance of many small rice grain pimples on the face can be considered as a skin disease such as cornu rashes, acne or rosacea, which can be treated by general treatment, topical medication or systemic medication according to the characteristics of the lesions. 1. Corns: The epidermis can be punctured with a needle after local disinfection to remove the yellowish-white cysts, or localized lesions can be removed using laser or electrodesiccation. 2. Acne: Pay attention to exfoliation and dissolution of keratin, and avoid scratching and squeezing the lesions; in mild cases, only topical medications such as Vitamin A cream, benzoyl peroxide, fusidic acid cream, azelaic acid and other preparations can be applied; in severe cases, systemic medication is used at the same time, and antibiotics (such as doxycycline), isotretinoin, and other medications are used to treat the lesions. 3. Rosacea: at this time, it is necessary to avoid excessive cleansing of the skin, pay attention to moisturizing as well as sunscreen, dietary control; inflammatory lesions can be used antibiotics such as clindamycin or erythromycin, benzoyl peroxide or azelaic acid cream, etc.; can be systematically applied to anti-microbial preparations such as doxycycline, with papules and pustules can be taken isotretinoin treatment. More acne on the face, you can promptly consult a doctor, after clarifying the cause of the disease, under the guidance of the doctor standardized treatment. The above drugs should be used according to the doctor’s instructions.