Human papillomavirus (HPV) is a group of viruses that are widely found in nature. Human infection with this virus is very common and the infection rate is high, with 20% to 80% of the sexually active population having a history of HPV infection. Although the majority of the population is transiently infected, it is worth noting that it is important for a family to prevent cross-infection with HPV within the family, especially when there are elderly people and children who have lower immunity. HPV virus is resistant to cold but not heat, in dry ice temperature (-70 ℃) and liquid nitrogen temperature (-196 ℃), the virus infectivity can remain for months to years, in -20 ℃ environment can survive 2 to 5 months, below 40 ℃ can survive a few days, in a dry environment can also survive longer, but in 50 ℃ ~ 60 ℃ after 30 minutes, or 100 ℃ a few seconds can be inactivated. x-ray, γ X-rays, gamma rays and ultraviolet light can inactivate the virus. Some common disinfectants, including ethanol, isopropyl alcohol, and glutaraldehyde products, are unable to inactivate the virus, but HPV is vulnerable to other chemicals such as hypochlorous acid and peroxyacetic acid. Therefore, households can be disinfected with disinfectant solutions containing chlorine or peroxyacetic acid, such as the common 84 disinfectant. If a family member is infected with HPV, in order to prevent cross-infection, it is important to do the following in daily life: 1. Fix sexual partners. The HPV is particularly prone to survive and proliferate in a warm and humid environment, so the external genitalia of both sexes are the most susceptible site for infection. The male circumcised can be circumcised to help prevent infection; women with cervical inflammation should also be treated in time to improve cervical resistance. 2, pay attention to the cleanliness of the family interior, to prevent pollution of clothing and other household items. The patient’s underwear should be washed separately, disinfected by hot water or soaked in chlorine disinfectant, and then exposed to sufficient direct sunlight for more than half an hour after cleaning. Do not mix clothes with those of children and other family members; disinfect and isolate hygiene products such as towels, bath towels, toothbrushes, razors, etc.; sleep in separate beds for adults and children; wash bedding regularly; use separate bath tubs and washbasins; scrub and disinfect toilet rings every day. Household washing machines can be disinfected with 84 disinfectant once every two or three months. Because HPV is infected through broken skin and mucous membranes, the main means of transmission is still sexual transmission, so daily contact such as eating, shaking hands, hugging, using common office utensils, household facilities, etc. is not infected. 3, HPV patients should maintain a healthy lifestyle, do not smoke and drink, improve their immunity. Wash your hands before and after going to the toilet, pay attention to the cleanliness of your hands and do not bring the virus in and out. Women should not douche their vagina and do not abuse antibiotics, otherwise it will destroy the vaginal micro-ecological environment and reduce the self-clearance rate of HPV virus. Usually, you only need to clean your vulva with water, do not wear tight, chemical fiber underwear, use sanitary pads as little as possible, change your underwear and wash it in time to keep your private parts dry and fresh. Men should choose cotton, loose fitting boxer briefs, not tight pants, and do not wash underwear with socks, but wash and disinfect them separately. Finally, HPV positive patients need to regularly go to the hospital to review, if the long-term infection of HPV virus is always unable to self-clear, but also need to timely medical treatment to prevent aggravation of the disease.