Decrease in blood pressure in hemodialysis patients may be related to decreased blood volume, taking antihypertensive drugs, and cardiac insufficiency. It can be dealt with by volume expansion therapy, stopping antihypertensive drugs, medication and so on. 1. Decrease in blood volume: When doing hemodialysis, blood volume decreases due to the large amount of water discharged from the body, and the phenomenon of decrease in blood pressure will occur. You can give rehydration and volume expansion treatment to raise blood pressure. 2. Taking antihypertensive drugs: if the patient takes antihypertensive drugs before hemodialysis, the water in the patient’s body will be reduced during dialysis, which will lead to a more obvious drop in blood pressure. On the day of dialysis, antihypertensive drugs should be stopped or reduced to avoid the occurrence of hypotension during dialysis. 3. Cardiac insufficiency: If the patient has cardiac insufficiency, dialysis will lead to insufficient ejection of blood from the heart, which will lead to low blood pressure. Pressure-raising drug therapy can be carried out, and commonly used drugs include dopamine hydrochloride injection, norepinephrine bitartrate injection and so on. Hemodialysis patients with decreased blood pressure is recommended to take specific drugs as prescribed by the doctor, and actively cooperate with the doctor to standardize the treatment.