How is g6pd deficiency diagnosed

g6pd deficiency refers to glucose-6-phosphate dehydrogenase deficiency. Clinical manifestations include anemia, soy sauce urine, jaundice, etc. Laboratory tests include quantitative determination of erythrocyte G-6-PD enzyme activity, etc., which should be diagnosed by the doctor according to the individual’s comprehensive assessment. 1. Hemolytic symptoms: in acute cases, anemia, fatigue, soy sauce urine, yellowing of the skin and sclera may appear in a short period of time, which may be accompanied by chills, fever and other symptoms, with a certain degree of self-limitation, and there are more males than females. Chronic patients can persist in different degrees of anemia, splenomegaly and other symptoms, accompanied by infection, the symptoms are aggravated. 2. Different causes: there are certain triggering factors for the onset of the disease, such as fava bean disease, which can occur when the mother consumes fava beans and the baby sucks breast milk; recent viral or bacterial infections, such as pneumonia, etc.; pediatric exposure to naphthalene-containing anthelmintic agents, such as mothballs, etc., can induce acute hemolysis and lead to g6pd deficiency. 3. Laboratory diagnosis: quantitative measurement of G-6-PD enzyme activity is a specific diagnostic indicator, and non-specific indicators can assist in the diagnosis, such as enzyme activity measurement, fluorescence spotting test and so on. There may be other methods to confirm the diagnosis of g6pd deficiency, such as blood bilirubin, GSH content measurement, etc. It is recommended to improve the examination under the guidance of a doctor to clarify the cause of the disease, and then standardize the treatment under the guidance of a physician.