Metformin extended-release tablets are mostly seen in the size of 0.5g per tablet, and the best way to take three tablets a day is to take three tablets once a day with dinner. The exact method of taking the medication should be consulted with your doctor and will depend on your individual situation. Metformin extended-release tablets can improve insulin resistance, applicable to patients with type 2 diabetes mellitus whose dietary control alone is unsatisfactory, especially obese people, may also have the effect of weight loss. The initial dose of metformin extended-release tablets is 0.5g once daily with dinner. If blood sugar control is not satisfactory, the dose may be increased gradually. Common adverse effects of this drug include nausea, fatigue, weight loss, dizziness, rash, etc. It is contraindicated in patients with type 2 diabetes mellitus with ketoacidosis, hepatic and renal insufficiency, pulmonary insufficiency, and heart failure. Metformin hydrochloride extended-release tablets of different specifications, dosage shall be determined by the doctor according to the patient’s condition, blood glucose and urinary glucose and other test results to determine the medication program, the patient should follow the doctor’s instructions to use, do not unauthorized use of medication, so as not to jeopardize the health of the body.