Uterine plus ovarian adnexectomy, which is technically more difficult, complicated and risky, can be categorized as major surgery. Uterine plus ovarian adnexectomy is mostly applied to uterine tumors, uterine bleeding, ovarian tumors, tubal lesions, etc. The scope of resection of this procedure is wide, including uterus, ovaries, fallopian tubes and other lesions. Intraoperative problems such as adhesion, bleeding, and tumor embeddedness may occur, thus increasing the difficulty of surgery. There is a risk that the surgery may cause damage to the ureter and bladder. Depending on the location of the lesion, the scope of hysterectomy and adnexectomy varies and includes three main categories: partial excision, subtotal excision and total excision. Depending on the size and nature of the lesion, the procedure can be performed transabdominally, laparoscopically or transvaginally. There are some differences in surgical difficulty and surgical operation between the different scope and route of operation. In case of uterine and adnexal lesions, it is important to consult a doctor in time for a clear diagnosis and to cooperate with the doctor to carry out surgical treatment as soon as possible.