In fact, itchy skin directly caused by hyperthyroidism is very rare in clinical practice. In most cases, itchy skin occurs after taking oral antithyroid medication for hyperthyroidism, mostly after taking Sage or propylthiouracil. It is usually recommended to stop or change to another antithyroid medication and to take oral anti-allergy medications such as levocetirizine and loratadine. If it is really itchy, you can also use topical anti-itch medications such as glyburide lotion. In short, you should always observe your body’s reaction to the medication during the treatment process, and if you can’t tolerate it, it is recommended to go to the hospital in time. If the itchy skin and rash feelings are still not relieved by using the above methods, it is recommended to stop the medication and you can switch to homoeopathic treatment or surgical treatment.