Rib pain in the liver area can be seen in normal people, but it may also be caused by liver and gallbladder diseases, pleurisy, intercostal neuralgia and other diseases, patients should consult a doctor in time. 1. Physiological conditions: if the pain in the rib cage in the liver area occurs after strenuous exercise and loud talking, it should be considered as a gas (i.e., local muscle spasm), which generally does not require special treatment. 2. Liver and gallbladder diseases: common liver and gallbladder diseases that can cause hepatic tenderness include cholecystitis, cholangitis, liver abscess, hepatitis, etc. In addition to hepatic tenderness, these patients will also have fever, change of stool color and other symptoms. 3. Pleurisy: inflammation caused by bacteria and other pathogenic factors invading the pleura, when occurring in the liver area near the ribs, there will be localized vague pain, cough, fever and other symptoms. 4. Intercostal neuralgia: pain in one or more intercostal nerve innervation areas caused by various reasons, which can be manifested as vague pain in the ribs of the liver area. It is necessary to go to the hospital in time, to clarify the diagnosis and treatment plan, to use drugs under the guidance of the doctor, and to avoid self-medication.