The side effects of Atractylodes macrocephala are as follows: 1. Atractylodes is bitter, warm and dry, which means that it should not be used for a long time by patients with fire, because it is warm; 2. Atractylodes can dispel dampness, which means that it is a dry drug, and it is not suitable for patients with yin deficiency, because dryness can harm yin and blood, and patients with yin deficiency and blood deficiency are not suitable for using Atractylodes; 3. Raw Atractylodes has a laxative effect, and patients with poor spleen and stomach or severe spleen deficiency are recommended to use fried Atractylodes instead of raw Atractylodes.