This is a topic that I have always wanted to talk about and have hesitated to do so. I don’t want patients to think that their doctors are advocating surgery, and I don’t want to add to the regrets of patients who have already missed out on surgery. So I will only talk about statistics and research findings here. Data from nearly 1,000 cases in the last 3 years show that the average Parkinson’s patient treated with surgery in our hospital has had the disease for 10 years and has a grade 3 or higher. This means that many patients come to surgery with unsteady walking, slurred speech, or choking on water, and what most of them don’t think about is that the best time for surgery has already been missed by then. Zhang Yuqing, Department of Functional Neurosurgery, Xuanwu Hospital, Capital Medical University There is a ‘honeymoon’ period for Parkinson’s patients, about 3 years, after 3 years, even if you increase the amount of medication, the effect is also reduced, so persist until the 4th to 6th year, it should be the best time for surgery, this is the joint report of several international research institutions, but also our experience. It is our experience that it is better to operate before balance disorders and dysphonia/swallowing difficulties appear, rather than wait for 10 years, for better long-term treatment results. However, we still often encounter patients who come in wheelchairs, have difficulty speaking and eating, and see surgery as a last hope. Some of them really didn’t know about surgery before, but many of them knew about it, but they just wanted to put it off as long as possible until they couldn’t put it off any longer, and as a result, the treatment was delayed. This is particularly regrettable. Of course, this is also our responsibility as doctors, not to pass on the international consensus reached a few years ago to those patients who are suitable for surgical treatment in a timely and accurate manner. Despite the hesitation, I am writing this article so that we can all have fewer regrets in the future. This article is published with the permission of Dr. Yuqing Zhang.