CT examination of giant cell tumor of bone can clearly show the bony shell, the inner surface of the shell is uneven, there is no real bony septum in the tumor, and the density inside the tumor is uneven, with areas of low-density necrosis visible, and sometimes a fluid-fluid plane is visible. The junction between the tumor and the bone cancellous mass was clear, but there was no osteophytic sclerosis. Giant cell tumor of bone is a kind of locally aggressive tumor, most of the giant cell tumor of bone is benign tumor, very few giant cell tumor of bone is malignant at the beginning. In China, giant cell tumor of bone is one of the common bone tumors, second only to osteochondroma in the incidence of benign bone tumors, and can often be diagnosed by X-ray, CT, MRI and other examinations. When symptoms related to giant cell tumor of bone appear, it is recommended to go to hospital for diagnosis and treatment as soon as possible to avoid delaying the condition.