The difference between liver function and two-and-a-half pairs is reflected in the following two aspects: 1, the significance of the response is different, liver function as the name implies the functional state of the liver, the response is the presence of inflammation, synthesis, metabolism of the liver, the main indicators are glutamic aminotransferase, glutamic oxalacetic aminotransferase, bilirubin, etc.; two-and-a-half pairs refers to the generic name of hepatitis B virus antigen antibody markers, reflecting the body’s reaction to infection with hepatitis B virus, the main indicators are surface antigen, surface antibody, e antigen and other five. The main indicators are surface antigen, surface antibody, e antigen and other five. 2, liver function and two to half have a causal relationship, but not only causal relationship, such as liver function abnormalities, may be caused by two to half abnormalities, but liver function abnormalities and other reasons, such as drug, metabolic are related; there is also the hepatitis B virus carrier two to half abnormal, but liver function is normal.