If a young person’s bilirubin of 29 μmol/L is due to physiological factors such as alcohol consumption and exercise, no special treatment is needed. If it is caused by hemolytic anemia, gallstones and other diseases, medication and surgery are needed to treat the cause. The normal value of total bilirubin is between 1.71-17.1umol/L. Young people’s bilirubin of 29μmol/L is on the high side. 1. Physiological factors: long-term alcohol consumption and strenuous exercise can lead to elevated bilirubin, which does not require special treatment. They can recover on their own after resting for a while and adjusting their lifestyles. 2. Hemolytic anemia: patients need to follow the doctor’s instructions to apply methylprednisolone, dexamethasone and other glucocorticoids. If glucocorticosteroids are contraindicated, immunosuppressants such as cyclophosphamide, azathioprine and mertiomacrophenol should be applied according to doctor’s instructions. Intravenous 5% sodium bicarbonate is also needed to protect renal function. For patients with severe disease, surgical treatment such as splenectomy and allogeneic hematopoietic stem cell transplantation should be considered. 3. Gallstones: patients need to follow the doctor’s instructions to apply diclofenac, indomethacin, ketoprofen and other non-steroidal anti-inflammatory drugs, can relieve pain. It is also necessary to follow the doctor’s instructions to apply ursodeoxycholic acid tablets and other choleretic drugs. If biliary colic recurs, surgical treatment such as laparoscopic cholecystectomy needs to be considered. There are many causes of bilirubin 29μmol/L in young people. If physiological elevation is excluded, further examination is needed to clarify the cause of the disease and standardize the treatment with the doctor.