Kidney qi insufficiency and kidney essence insufficiency are different in clinical manifestations, treatment principles, and therapeutic prescriptions. For the clinical symptoms of kidney qi insufficiency, such as weakness of muscles and bones, shortness of breath, etc., it is necessary to warm up the kidney qi and take Jin Gui Kidney qi Pills orally; for the clinical symptoms of kidney essence insufficiency, such as spermatorrhea and urination, lumbar and knee soreness, etc., it is necessary to nourish yin and fill up the essence, and take Zuo Gui Pills orally for the treatment. 1. Clinical manifestations: For the clinical symptoms of Kidney Qi deficiency, there are symptoms such as weakness of muscles and bones, shortness of breath, dribbling of urine or swelling of urine; for the symptoms of Kidney Essence deficiency, there are symptoms such as spermatorrhea and enuresis, soreness and weakness of waist and knees (feeling of soreness and weakness of waist and knees), heat of hands and feet, forgetfulness and insomnia. 2. Treatment principle: clinically, kidney qi deficiency is often seen together with kidney yang deficiency (lack of yang qi of the kidney), so the treatment is based on warming and tonifying the kidney qi, inducing diuresis and eliminating oedema; for kidney essence deficiency, it is often seen together with deficiency of kidney yin, so it is based on the principle of nourishing yin and clearing heat (nourishing the yin essence and removing the heat evils), and filling up essence to stop ejaculation (filling up the essence to prevent spermatorrhea and seminal emission). 3. Therapeutic prescriptions: For patients with deficiency of kidney qi, Jin Gui Ren Qi Pill and Right Angelica Pill are often applied for treatment; for deficiency of kidney essence, Zuo Gui Pill or Liu Wei Di Huang Wan are often applied for treatment. Kidney qi deficiency and kidney essence deficiency are different in the above aspects, so it is recommended that patients with kidney deficiency consult a regular hospital in a timely manner, under the guidance of the doctor’s diagnosis and treatment with medication, do not take medication on your own to delay the condition.