Cirrhosis is a pathological stage characterized by chronic liver inflammation, pseudofollicular formation, diffuse fibrosis, etc., which is progressed by various chronic liver diseases, and hepatocellular carcinoma can be secondary to cirrhosis or hepatitis and other etiologies.
Cirrhosis is mainly dominated by hepatitis B virus infection in China, and can also be related to cholestasis, genetic metabolic diseases, parasitic infections, circulatory disorders and other etiological factors. Pathogenic factors activate hepatic astrocytes, resulting in diffuse fibrosis as well as formation of pseudofollicles in the liver, thus causing cirrhosis.
Hepatocellular carcinoma can be related to various etiologic factors such as cirrhosis, aflatoxin, viral hepatitis or chemical carcinogens, which cause cancerous transformation of hepatocytes or bile duct epithelial cells.
Once cirrhosis and hepatocellular carcinoma are detected, one should consult a doctor in time and take active treatment to slow down the progress of the disease.