Itchy around the anus at night, first to the anorectal examination is what causes anal itching, in order to choose the right treatment of drugs, the common clinical anal itching is perianal eczema and intestinal parasites. The perianal eczema treatment can be a 1:5000 ratio of potassium permanganate powder to water sitz bath, then use a clean, dry towel to dry the anus, local rubbing Ma Yinglong hemorrhoid cream treatment, usually avoid spicy, stimulating food, keep the anal area clean, dry, avoid sedentary. The diagnosis of perianal eczema is mainly based on anal itching, slight odor, and relatively dampness around the anus, which can be judged through anorectal interview and medical history. If it is intestinal parasites, treatment requires oral deworming medication. The commonly used deworming medication is albendazole tablets, which should be taken once at night before going to bed. Intestinal parasites also cause anal itching, which tends to itch at night, and there are no obvious changes in the pathological features around the anus.