The two most effective routes of administration are intravenous infusion and topical application. Intravenous infusion is a method of administering drugs through intravenous drips or injections into the body’s blood circulation, and then reaching the site of action with the blood circulation. Since intravenous infusion works with the body’s blood circulation, it does not have the first pass elimination effect of oral drugs, so it works quickly and maintains its efficacy relatively well. Topical drugs are applied directly to certain parts of the body, such as infections or swelling caused by trauma. Since the drug acts directly on the diseased area, the effect of the drug is faster. The route of administration varies from drug to drug, some drugs can only be applied intravenously, while others can only be used externally, so the best route of administration needs to be chosen in relation to the specific disease and the chemical principle of the drug itself.