Heartburn caused by medication is likely to be caused by this gastric drug gastric mucosal damage or the opening and closing of the pylorus of the stomach is not functioning well, resulting in bile reflux upward due to the above symptoms, the patient needs to be asked to take medication in order to roughly determine which drug causes heartburn, if the symptoms are more serious, the need to stop using this drug, and at the same time, replace it with other medications. When a patient has heartburn, mild cases can be treated with medications such as omeprazole plus trimethoprim maleate. If the symptoms are not relieved for three days after the medication, an electronic gastroscopy is needed to rule out other pathologies, such as the development of ulcers in the stomach and duodenum, which need to be controlled with medications such as Rehabilitation New Liquid plus Eprazole.