The presence of fecal and bloody discharge in the vagina is due to the fact that the cancer of the anterior rectal wall in women can infiltrate the posterior vaginal wall when it penetrates the intestinal wall, causing increased leucorrhea; if it penetrates the posterior vaginal wall, it forms a rectovaginal fistula, thus causing fecal and bloody discharge in the vagina. This is one of the clinical symptoms of rectal cancer. What is the differential diagnosis of fecal and bloody discharge in the vagina? Let’s take a look at them. Differential diagnosis of fecal matter and bloody secretion in the vagina 1. The differential diagnosis of colon cancer is mainly the inflammatory diseases of the colon, such as intestinal tuberculosis, schistosomiasis, sarcoidosis, amoebic granuloma, ulcerative colitis and colonic polyposis. The main points of clinical differentiation are the length of disease, fecal examination for parasites, the morphology and extent of lesions seen by barium enema, etc. The most reliable differentiation is by colonoscopy with biopsy. Periappendiceal abscess can be misdiagnosed as cecum cancer (colon cancer), but the blood picture of this disease has high white blood cells and neutrophils, no anemia, wasting and other cachexia, and barium enema examination can make a clear diagnosis. 2. Rectal cancer is often misdiagnosed as hemorrhoids, bacterial dysentery, chronic colitis and so on. The misdiagnosis rate is as high as 60% to 80%, which is mainly due to the lack of necessary examinations, especially anal finger diagnosis and proctoscopy. Other tumors of the colon, such as colorectal carcinoid tumors, are asymptomatic when the tumor is small, but can break down when the tumor grows large, showing symptoms very similar to colon adenocarcinoma; malignant lymphoma originating from the colon, with a variety of lesion patterns, is often not easy to distinguish from colon cancer. All of them should be distinguished by tissue smear biopsy.