There are more causes of pain in the middle of both eyebrows in children, which may be related to primary headache such as migraine, cluster headache and tension headache, or secondary headache such as herpes zoster, eye disease and sinusitis. I. Primary headache: 1. Migraine: generally related to family genetics, also can be triggered by eating cheese, chocolate, pickles, cured meat, etc. Some children can show pulsating throbbing pain in the middle of both eyebrows, usually accompanied by nausea, vomiting, fear of sound and light, ibuprofen can be given for pain relief, and those who cannot be relieved can be treated with calcium channel blockers such as flunarizine hydrochloride capsules under the guidance of doctors, and can also The symptoms can also be improved by resting. 2. Cluster headache: Mostly seen in boys, it is caused by autonomic dysfunction of the trigeminal nerve, which manifests as severe periorbital pain, and can also appear in the middle of both eyebrows, requiring pure oxygen inhalation and, if necessary, ibuprofen under the guidance of a doctor. 3. The main manifestation is distension and pain in the middle of both eyebrows, which can be relaxed by local physiotherapy and massage, and the symptoms can also be improved by rest and sleep. Secondary headache: 1. Herpes zoster: it is caused by viral infection, if it appears on the head and face, it may cause stabbing pain in the center of both eyebrows, which may be accompanied by herpes, and ibuprofen can be given to improve the symptoms, together with the use of antiviral drugs; 2. Eye diseases: if children suffer from glaucoma, it may cause an increase in intraocular pressure and headache in the middle of both eyebrows, which mostly requires surgery; 3. suffer from sinusitis, such as frontal sinus inflammation stimulation, may cause symptoms of pain in the center of both eyebrows, and need to be treated with sensitive antibiotics; 4, intracranial lesions: intracranial lesions mainly include encephalitis and intracranial tumors, etc., which may cause pain in the middle of both eyebrows, and need to be treated for the cause. When children develop fever or upper respiratory tract infection, it may also cause pain in the middle of both eyebrows secondary to fever. If the symptoms are severe, such as high body temperature, hoarseness, and severe headache, prompt medical attention is needed for targeted treatment.