Pressing pain above the sternum is commonly caused by costochondritis, which may also be caused by rib fracture, malignant tumor infiltration of sternum and other diseases, and it is recommended to go to the hospital for relevant examination in time. 1. Costal chondritis: costal chondritis will cause pressure pain above the sternum, the pain will be more obvious when it is collided or squeezed, some patients may have redness and swelling of the skin at the affected area, accompanied by burning sensation of varying degrees, the pain is radiating, and it may make the back feel uncomfortable. 2. Rib fracture: there is often a history of injury, pain may occur when deep breathing or holding out the chest, accompanied by localized obvious pressure pain, chest X-ray can be seen in the bone cortical discontinuity. Some patients may have shortness of breath or restricted breathing due to pain. 3. Malignant tumor infiltrating the sternum: in the advanced stage of malignant tumor, the tumor invades the sternal ribs, and there may be pressure pain on the sternum and ribs, accompanied by cough, hemoptysis, emaciation and other symptoms. Pressing pain above the sternum may also be hematologic diseases. Pressing pain above the sternum needs timely medical treatment, through the examination to clarify the cause of the disease, according to the doctor’s advice, choose the appropriate treatment to avoid delaying the condition.