There is no such thing as the most accurate test for bone tuberculosis, and the diagnosis usually needs to be made by combining the patient’s medical history, clinical symptoms, and examination results. 1. Patient’s medical history: history of contact with tuberculosis or primary foci of tuberculosis. 2. Clinical symptoms: Bone tuberculosis has many symptoms, with the development of the disease, there may be generalized fatigue, low fever in the afternoon, night sweats (sweating abnormally after going to sleep, and sweating stops after waking up), loss of appetite, weight loss, etc.; locally, there may be pain at the site of onset, swelling, cold abscesses, and dysfunction. 3. Imaging and bacteriological examination: the imaging features of tuberculosis, such as bone destruction, local abscess formation, narrowing of the joint space, dead bones, paravertebral shadows, etc., can be examined by X-ray, CT, MRI, etc.; or bacteriological findings of tuberculosis, positive tuberculin test; or combined with local biopsy and puncture, and tuberculosis bacilli are found in the puncture material, can be confirmed diagnosis of tuberculosis of bone.