If a patient misses a dose while taking Mafron for the treatment of the disease, the appropriate treatment plan should be chosen depending on the time of the missed dose. If the missed dose occurs during the third week of treatment, the patient may choose to stop taking the medication and start a new cycle of taking the medication after the onset of menstruation. Since the drug cycle is coming to an end and the drug has been in the body for a long time and has reached a certain concentration, stopping the drug will not have a significant impact on treatment. If the patient does not miss a dose in the third week, he or she may choose to take a top-up dose, that is, an oral dose in the morning of the day after the missed dose. Occasional missed doses do not affect the therapeutic effect, but they should not be missed continuously to avoid the condition of vaginal bleeding.