Milled glass nodules include mixed milled glass nodules and pure milled glass nodules. Mixed and pure milled glass nodules differ in terms of density, risk of malignancy, and management. 1. Density: Mixed ground-glass nodules contain both solid and ground-glass components, also known as partially solid nodules; pure ground-glass nodules have only ground-glass components. 2. Risk of malignancy: Both can be caused by either benign diseases such as inflammation of the lungs or malignant diseases such as lung cancer. Among the ground-glass nodules, the malignant risk of mixed nodules is higher than that of pure ground-glass nodules, and an increase in the number or size of mixed ground-glass nodules during follow-up suggests that malignant changes may exist. 3. Treatment: Because of the different risk of malignancy between the two, the frequency of follow-up is different. For example, pure ground-glass nodules can be reviewed after 6 to 12 months, and if the nodules are stabilized, they can be reviewed once every two years; mixed nodules need to be reviewed after 3 to 6 months, and annually after the nodules are stabilized. It is recommended that patients consult a specialist and make a comprehensive judgment based on other descriptions of the size, shape and margins of the nodule, and follow the doctor’s instructions for further examination and treatment.