There is no up-to-date treatment for polycystic kidney. However, several recent studies have shown that tolvaptan (arginine pressin V₂ receptor antagonist) can delay the increase in kidney size and deterioration of renal function in patients with polycystic kidney, but this drug is more costly and the effect is not so certain, so it needs to be used in accordance with the doctor’s prescription. Polycystic kidney, also known as autosomal dominant nephropathy, is a hereditary disease, caused by genetic mutations, there is no direct cure, but can only inhibit the growth of cysts and slow the decline of renal function. Several studies have shown that drugs such as tolvaptan can inhibit the growth of cysts. The most common adverse reactions of tolvaptan include thirst, fatigue, constipation, polyuria, hyperglycemia, etc. It is prohibited for those who are allergic to this product, suffering from anuria, hypernatremia, etc. It is also used with caution for those who are suffering from hyperkalemia, hepatic encephalopathy, severe cerebrovascular diseases, etc. If you need to take tolvaptan for polycystic kidney disease, you should use it under the guidance of professional doctor, do not use it by yourself. It is recommended that patients go to the hospital in time and follow the doctor’s instructions for standardized treatment.