When male infertility is present, the treatment with stem cell spermatogenesis technology is more effective and has a therapeutic effect for some patients, but for some patients, the effect is limited. For patients with oligospermia and weak spermatozoa, the use of this technology can achieve good therapeutic results and help male patients restore their reproductive ability. However, for patients with malignant tumors that require adjuvant radiotherapy or patients with lesions in the male reproductive organs themselves, stem cell spermatogenesis has a limited effect and cannot solve the fundamental problem, and other assisted reproductive techniques can be used to help get pregnant, such as artificial insemination. When men experience infertility, it is recommended that they seek timely medical attention to clarify the cause of the disease, reduced sperm quality and quantity, and lesions of the reproductive organs leading to infertility, and choose the appropriate treatment plan under the guidance of the doctor.