Dapoxetine hydrochloride is a drug for the treatment of premature ejaculation, and its price difference is mainly due to the difference between imported drugs as well as domestic drugs. 1. Imported drugs: Dapoxetine is currently an expensive imported drug. 2. Domestic drugs: With the lifting of the ban on drug production technology, the domestic production of approved generic drugs, due to the different manufacturers, production and transportation costs are reduced, relatively speaking, the price is much cheaper. The effects of domestic generic drugs are the same as those of imported drugs. The drug is contraindicated in people with a known hypersensitivity to the drug, in patients with a significant pathological condition of the heart, in patients with moderate and severe liver damage. The drug is also not to be used in conjunction with thioridazine, strong cytochrome P450 3A4 inhibitors, and monoamine oxidase inhibitors. Dapoxetine is a prescription drug and needs to be used under the supervision of a doctor. You may experience dizziness, headache, nausea, and vomiting after use.