Brown patches in the esophagus may be caused by bile reflux gastritis, esophageal melanosis, esophageal melanoma, etc. They usually need to be treated with drugs such as magnesium aluminum carbonate, ursodeoxycholic acid, or surgery. 1. Bile reflux gastritis: It may be due to bile reflux gastritis, which causes bile to reflux into the esophagus and stagnate into the esophagus, which in turn causes brownish plaques to appear in the esophagus. It can be treated with magnesium aluminum carbonate tablets, ursodeoxycholic acid capsules and other medicines as prescribed by the doctor. 2. Esophageal melanosis: usually due to esophageal melanosis, the melanocytes of the esophageal mucosa are increased and deposited, and appear brown to the naked eye, which leads to the appearance of brown patches. Generally, no special treatment is needed, you can go to the hospital regularly for review, and eat vitamin-rich food in moderation. 3. Esophageal melanoma: It is generally due to the repeated stimulation of melanin in the esophagus and causes esophageal melanoma, which leads to a large number of melanocytes in the esophagus proliferating and accumulating, and then brown plaques appear in the esophagus. It can be treated with surgery such as total esophagectomy and esophageal tumor resection. If the esophagus appears brown plaque situation, should promptly go to the hospital for examination, under the judgment of the doctor targeted treatment.