Some difficulty in the middle of the chest, indicating hidden pain, pain under the raphe, etc., may be a combination of gallbladder stones and chronic inflammation of the gallbladder. When there are stones in the gallbladder, it can lead to inflammation of the gallbladder wall, which can manifest as discomfort such as vague pain and distension in the upper abdomen as well as pain in the right upper abdomen. It may be accompanied by nausea, vomiting or anorexia, and the pain may worsen after eating fatty foods. An ultrasound of the liver and gallbladder is needed to visualize the inside of the gallbladder, and if stones can be detected in the gallbladder, laparoscopic cholecystectomy is recommended. If there are no stones in the gallbladder, the pain may be caused by gastric diseases, such as chronic gastritis or gastric ulcer. Gastroscopy can be performed, usually can be clearly diagnosed, gastroscopy is more intuitive, can find the mucosal lesions in the stomach is inflammatory lesions or ulcerative lesions. After the diagnosis is clear, oral medication is recommended, such as omeprazole, clarithromycin, amoxicillin and so on.