If you take roxithromycin in the morning, whether you can drink alcohol in the evening, this question cannot be generalized and requires specific analysis. Patients who do not have previous allergy to roxithromycin, and who have not had alcohol allergy or alcoholism, can basically drink alcohol in the evening after 12 hours of metabolism after taking roxithromycin in the morning and after half-life metabolism, but they should drink alcohol in small amounts, because alcohol consumption has adverse effects on pharmacokinetics and absorption and digestion of the drug. If there is a previous allergy to roxithromycin or there is an alcohol allergy, it is not recommended to drink alcohol in the evening immediately after taking roxithromycin in the morning, because alcohol will accelerate the allergic reaction of the body, which will lead to chronic allergy and secondary drug reactions to the drug, which will cause nausea, vomiting, regurgitation, acid reflux and other adverse conditions.