There are several factors that contribute to high inflammatory markers: First, the most common factor is infection, which can produce clinical symptoms of high inflammatory markers in the body when the body is infected with bacteria, viruses, fungi and other atypical pathogens such as mycoplasma and chlamydia. Second, non-infectious factors such as connective tissue disease, rheumatoid arthritis, rheumatoid arthritis, dermatomyositis, systemic lupus erythematosus, and dry syndrome can also produce high inflammatory indexes in the body. Third, when endocrine diseases, such as adrenocortical insufficiency, hypothyroidism, also appear relatively high inflammatory index. Fourth, diseases with extremely low immunity, such as severe anemia, tumors, and AIDS, can also produce high inflammatory indexes in the body.