Polyene phosphatidylcholine and silymarin do not have a good saying, should be based on the patient’s specific situation and indications, etc., symptomatic use of drugs. Due to the different mechanisms, indications, adverse effects and contraindications of the two drugs, there is no better, according to the patient’s specific situation, the patient should choose the appropriate drug for treatment. 1. Polyene phosphatidylcholine: a liver therapeutic drug. The mechanism of action is to protect and stabilize the cell membrane of liver cells and organelles. It is used to assist in improving toxic liver injuries such as those caused by drugs, poisons, chemicals and alcohol, as well as loss of appetite and right upper abdominal pressure in patients with fatty liver and hepatitis. Adverse Reactions Occasionally gastrointestinal disturbances such as upset stomach, diarrhea, rash, urticaria, and pruritus may occur at high doses. It is contraindicated in patients with known hypersensitivity to soy preparations, phosphatidylcholine and/or hypersensitivity to any of the ingredients in this product. 2. Silymarin: It is an anti-fatty liver drug with stabilizing effect on liver cell membrane, which can prevent or avoid the loss of soluble cellular components; stimulate the activity of RNA polymerase I in the nucleus of the cell to help the synthesis of ribosomal RNA in the liver cells; and enable the synthesis of structural and functional proteins (enzymes). Used for supportive treatment of toxic liver injury, chronic hepatitis and cirrhosis. Adverse Reactions Occasionally mild diarrhea has been noted. It is contraindicated for those who are allergic to the product. Patients should pay attention to rest, light diet, do not smoke and drink alcohol and stay up late, etc., pay attention to review liver function to understand the treatment.