Nowadays, many children in our society become cerebral palsy patients. At the same time, when a child suffers from cerebral palsy, his growth process will be greatly affected and he will also suffer a lot of pain. There are many causes of cerebral palsy, but those who cannot find the cause may be more than 1/3, and sometimes there may be multiple factors in some cases. 1. Prenatal factors are the most common, including genetic and chromosomal disorders, congenital infections, malformations or dysplasia of brain development, and fetal brain ischemia and hypoxia causing white matter softening around the ventricles or damage to the basal ganglia. Perinatal factors refer to brain injury that occurs between the beginning of labor and one week after birth, including cerebral edema, neonatal shock, intracerebral hemorrhage, sepsis or central nervous system infection, and ischemic-hypoxic encephalopathy. Perinatal factors may be an important cause of cerebral palsy in preterm infants. Factors after late neonatal period include various causes of non-progressive brain injury such as central nervous system infection, cerebrovascular disease, cranial trauma, poisoning, etc. occurring between 1 week and 3 or 4 years of age. 2. Although prematurity and intrauterine growth retardation are not direct causes of cerebral palsy, they are important high-risk factors for cerebral palsy. Intrauterine inflammation of the mother or chorioamnionitis, as a potential risk factor, has been increasingly appreciated. 3. Pathological changes are related to the etiology and the susceptibility of the developing brain to damage by various pathogenic factors. Early gestational pathogenic factors mainly cause abnormalities in neuronal proliferation and migration, which can lead to anencephaly, megalencephaly, polymicrocephaly, cerebral cleft malformation and neuronal ectopia. 4. The most common pathological changes in preterm infants are periventricular white matter softening and periventricular hemorrhagic infarcts. The type of pathology in full-term infants is complex and varied, often associated with hypoxic-ischemic brain injury. The marble state, on the other hand, is characterized by neuronal loss and gliosis in the basal ganglia and thalamus with increased myelination, resulting in a marble-like texture, typical of nuclear jaundice, also seen in hypoxic-ischemic brain injury. Every parent should understand the basic causes of cerebral palsy and take measures to deal with it so that their child does not become a cerebral palsy patient.