Cough with generalized weakness may be related to tuberculosis, cold and lung cancer. 1. Tuberculosis, dry cough, weakness is a typical symptom of tuberculosis, due to mycobacterium tuberculosis infection, can cause similar symptoms, need to carry out sputum culture, tuberculin test and other tests in order to clarify the diagnosis. 2. Cold and flu can also cause cough and fatigue, because the immune system needs to fight with the virus that causes cold and flu, which consumes a lot of energy and can cause fatigue, and at the same time, the virus damages the mucous membrane of trachea and bronchus, which can cause cough. 3. Lung cancer, due to the pressure of the tumor on the trachea and bronchial tubes, cough can be formed, and at the same time, the tumor consumes energy, which can cause symptoms of fatigue. Cough with generalized weakness may also be seen in bronchitis, pneumonia and other diseases, the specific causes need to be clarified after medical examination, and at the same time according to the doctor’s instructions for treatment.