The hard inside of the flesh of acne on the face is considered to be related to cystic acne, which belongs to severe acne and can be relieved by general treatment, medication and physical therapy. 1. General treatment: patients need to pay attention to the cleanliness of the lesion area, you can use mild water or cleansing milk to clean the face, pay attention to oil control and moisturizing, and avoid excessive scratching and squeezing with hands. 2. Treatment with medication: Vitamin A and antibiotics can be chosen as combination therapy, such as isotretinoin and minocycline, so as to control local inflammation and reduce the formation of scarring. 3. Physical therapy: For patients who are not effective in traditional treatment, physical therapy can be chosen, such as photodynamic therapy, which can rapidly improve the symptoms in a short period of time and reduce the post-inflammatory hyperpigmentation and scar formation. It is recommended that patients need to cooperate with doctors as soon as possible to clarify the cause and give standardized treatment, so as to reduce the patient’s symptoms, and must not blindly use drugs, so as to avoid adverse effects.